This is a urine test for the condition PYROLURIA also known as Pyrrole disorder, kryptopyroluria, kryptopyrole or Mauve disorder. It affects approximately 10% of the population but most people who have it will go undiagnosed and improperly treated, usually prescribed antidepressant medication.
Pyrroluria is a genetic defect in the metabolism of haemaglobin (the oxygen carrying part of blood) which creates excess waste products called pyrroles. These bind to zinc, B6, biotin and omega-6 fatty acids causing deficiencies in these nutrients. Symptoms of pyrroluria include -
anxiety/fear/panic pale skin/inability to tan
social phobia/isolation stretch marks
easily fatigued white spots on the nails
poor short term memory premature grey
pessimism dry skin depression light/sound/odour intolerance
low stress tolerance poor dream recall
explosive anger morning nausea/skips breakfast
hyperactivity motion sickness
Urine is collected in a darkened room and placed in a vial with a preservative and immediately frozen as pyrroles break down very rapidly in light.
Treatment involves supplementation of the missing nutrients, usually zinc and B6 is enough but it depends on the severity of the condition. Long term treatment should involve addressing the underlying causes.
Although this is usually a genetic condition, causes such as poor diet, environmental and emotional stress and especially ‘leaky gut syndrome’ and the over use of antibiotics need to be remedied.
Stress of any kind will increases production of pyrroles which in turn decreases zinc and B6. A person with pyroluria will find their symptoms worse during stress and will need to take higher doses of supplements during this time.
Stress doesn't have to be a looming deadline or exam, even a common cold is a stress on the body. One way to significantly reduce the effect of stress is to eat very regularly and maintain a stable blood sugar level.
Wholistic treatment of pyroluria looks at more than supplements and gives the knowledge and tools to the client so they understand and can manage their symptoms more effectively.